Präventive Onkologie 67
Berti E (2005) Inhibition of angiogenesis by potential Cancer chemopreventive agents - estab-
lishment of a human in vitro anti-angiogenesis assay and mechanistic evaluation of potent
inhibitors. Diss. Univ. Heidelberg, Medizinische Fakultät
Berti E, Kümo K, Heiss E, Klenke F, Peschke P, Becker H, Eicher T, Herhaus C, Kapadia G, Bartsch
H, Gerhäuser C (2004a) Identification of novel inhibitors of angiogenesis using a human in
vitro anti-angiogenesis assay. Intern J Cancer Prev 1:47-61
Berti E, Becker H, Eicher T, Herhaus C, Kapadia G, Bartsch H, Gerhauser C (2004b) Inhibition
of endothelial cell functions by novel potential Cancer chemopreventive agents. Biochem
Biophys Res Commun 325:287-295
Bingham SA, Day NE, Luben R, Ferrari P, Slimani N.Norat T, Clavel-Chapelon F, Kesse E.Nieters A,
Boeing H, Tjonneland A, Overvad K et al. (2003) Dietary fibre in food and protection against
colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition
(EPIC): an observational study. Lancet 361:1496-1501
Frank A, Seitz HK, Bartsch H, Frank N, Nair J (2004) Immunohistochemical detection of l,N6-
ethenodeoxyadenosinein nuclei of human liver affected by diseases predisposing to hepato-
carcinogenesis. Carcinogenesis 25:1027-1031
Gerhäuser C (2005) Beer constituents as potential Cancer chemopreventive agents. Eur J Cancer
41:1941-1954
Gerhäuser C, Klimo K, Heiss E, Neumann I, Gamal-Eldeen A, Knauft J, Liu GY, Sitthimonchai S,
Frank N (2003) Mechanism-based in vitro Screening of potential Cancer chemopreventive
agents. Mutat Res 523/524:163-172
Gerhäuser C, Alt A, Heiss E, Gamal-Eldeen A, Klimo K, Knauft J, Neumann I, Scherf HR, Frank
N, Bartsch H, Becker H (2002) Cancer chemopreventive activity of Xanthohumol, a natural
product derived from hop. Mol Cancer Ther 1:959-969
Gescher AJ, Sharma RA, Steward WP (2003) Cancer prevention and delay are as important as
eure. Lancet Oncol 4:72-73
Gissmann L (2003) Human papillomaviruses. In: The Vaccine book, BR Bloom, PH Lambert
(eds). Amsterdam Academic Press, 311-322
Hussong R, Frank N, Knauft J, Ittrich C, Owen R, Becker H, Gerhäuser C (2005) A safety study of
oral xanthohumol administration and its influence on fertility in Sprague Dawley rats. Mol
Nutr Food Res 49:861-867
Miller AB, Altenburg HP, Bueno-de-Mesquita B, Boshuizen HC, Agudo A, Berrino F, Gram IT,
Janson L, Linseisen J, Overvad K, Rasmuson T, Vineis P et al. (2004) Fruits and vegetables
and lung cancer: Findings from the European Prospective Investigation into Cancer and
Nutrition. Int J Cancer 108:269-176
Pan L, Becker H, Gerhäuser C (2005) Xanthohumol induces apoptosis in eultured 40-16 human
colon cancer cells by activation of the death reeeptor and mitochondrial pathway. Mol Nutr
Food Res 49:837-843
Riboli E (1992) Nutrition - and cancer: background and rationale of the European Prospective
Investigation into Cancer and Nutrition (EPIC). Ann Oncol 3:783-791
Riboli E (2001) The European Prospective Investigation into Cancer and Nutrition (EPIC): plans
and progress. J Nutr 131,170S-175S
Sporn MB, Suh N (2002) Chemoprevention: an essential approach to Controlling cancer. Nat Rev
Cancer 2:537-543
Sun X, Nair J, Bartsch H (2004) A modified immuno-enriched 32P-postlabeling method for an-
alyzing the malondialdehyde-deoxyguanosine adduet, 3-(2-deoxy-beta-D-erythro-pento-
furanosyl)-pyrimido[i,2-alpha]purin-io(3H)one in human tissue samples. Chem Res Toxi-
col 17:268-272
Berti E (2005) Inhibition of angiogenesis by potential Cancer chemopreventive agents - estab-
lishment of a human in vitro anti-angiogenesis assay and mechanistic evaluation of potent
inhibitors. Diss. Univ. Heidelberg, Medizinische Fakultät
Berti E, Kümo K, Heiss E, Klenke F, Peschke P, Becker H, Eicher T, Herhaus C, Kapadia G, Bartsch
H, Gerhäuser C (2004a) Identification of novel inhibitors of angiogenesis using a human in
vitro anti-angiogenesis assay. Intern J Cancer Prev 1:47-61
Berti E, Becker H, Eicher T, Herhaus C, Kapadia G, Bartsch H, Gerhauser C (2004b) Inhibition
of endothelial cell functions by novel potential Cancer chemopreventive agents. Biochem
Biophys Res Commun 325:287-295
Bingham SA, Day NE, Luben R, Ferrari P, Slimani N.Norat T, Clavel-Chapelon F, Kesse E.Nieters A,
Boeing H, Tjonneland A, Overvad K et al. (2003) Dietary fibre in food and protection against
colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition
(EPIC): an observational study. Lancet 361:1496-1501
Frank A, Seitz HK, Bartsch H, Frank N, Nair J (2004) Immunohistochemical detection of l,N6-
ethenodeoxyadenosinein nuclei of human liver affected by diseases predisposing to hepato-
carcinogenesis. Carcinogenesis 25:1027-1031
Gerhäuser C (2005) Beer constituents as potential Cancer chemopreventive agents. Eur J Cancer
41:1941-1954
Gerhäuser C, Klimo K, Heiss E, Neumann I, Gamal-Eldeen A, Knauft J, Liu GY, Sitthimonchai S,
Frank N (2003) Mechanism-based in vitro Screening of potential Cancer chemopreventive
agents. Mutat Res 523/524:163-172
Gerhäuser C, Alt A, Heiss E, Gamal-Eldeen A, Klimo K, Knauft J, Neumann I, Scherf HR, Frank
N, Bartsch H, Becker H (2002) Cancer chemopreventive activity of Xanthohumol, a natural
product derived from hop. Mol Cancer Ther 1:959-969
Gescher AJ, Sharma RA, Steward WP (2003) Cancer prevention and delay are as important as
eure. Lancet Oncol 4:72-73
Gissmann L (2003) Human papillomaviruses. In: The Vaccine book, BR Bloom, PH Lambert
(eds). Amsterdam Academic Press, 311-322
Hussong R, Frank N, Knauft J, Ittrich C, Owen R, Becker H, Gerhäuser C (2005) A safety study of
oral xanthohumol administration and its influence on fertility in Sprague Dawley rats. Mol
Nutr Food Res 49:861-867
Miller AB, Altenburg HP, Bueno-de-Mesquita B, Boshuizen HC, Agudo A, Berrino F, Gram IT,
Janson L, Linseisen J, Overvad K, Rasmuson T, Vineis P et al. (2004) Fruits and vegetables
and lung cancer: Findings from the European Prospective Investigation into Cancer and
Nutrition. Int J Cancer 108:269-176
Pan L, Becker H, Gerhäuser C (2005) Xanthohumol induces apoptosis in eultured 40-16 human
colon cancer cells by activation of the death reeeptor and mitochondrial pathway. Mol Nutr
Food Res 49:837-843
Riboli E (1992) Nutrition - and cancer: background and rationale of the European Prospective
Investigation into Cancer and Nutrition (EPIC). Ann Oncol 3:783-791
Riboli E (2001) The European Prospective Investigation into Cancer and Nutrition (EPIC): plans
and progress. J Nutr 131,170S-175S
Sporn MB, Suh N (2002) Chemoprevention: an essential approach to Controlling cancer. Nat Rev
Cancer 2:537-543
Sun X, Nair J, Bartsch H (2004) A modified immuno-enriched 32P-postlabeling method for an-
alyzing the malondialdehyde-deoxyguanosine adduet, 3-(2-deoxy-beta-D-erythro-pento-
furanosyl)-pyrimido[i,2-alpha]purin-io(3H)one in human tissue samples. Chem Res Toxi-
col 17:268-272